AMSBIO’s 30-years of experience in serving the glycobiology research community has led to an extensive portfolio of high-quality reagents that include unique varieties of enzymes, lectins and standards.
Hyaluronic Acid staining using HABP (b–VG1 green) of an extended cumulus oocyte compound in the mouse ovarian follicle. Blue is staining with DAPI. Image from Tony Day from University of Manchester, UK. Image credit: AMSBio
Glycobiology (the study of the structure, biosynthesis, and biology of carbohydrates) is an incredibly complex and dynamic field of research that blends enzymology, molecular and cellular biology, organic chemistry , and materials science. Glycobiology is a rapidly growing field of study that is widely recognized as being crucial for both cellular biology and the study of carbohydrate-based therapeutics as well as drugs.
Dr. William Hadlington Booth, Glycobiology product Manager, commented, “To maintain our global reputation as the most reputable supplier to the glycobiology research comunity We are constantly innovating leading-edge products and investing in our inventory to ensure researchers have access to the most important ingredients when they need them.”
AMSBIO has developed an unrivaled array of monoclonal antibodies and binding proteins to support proteoglycan, ganglioside (GAG), and ganglioside research such Heparan Sulfate. Chondroitin Sulfate. Keratan Sulfate. Hyaluronic Acid. The antibodies from AMSBIO are high in terms of specificity, affinity, and compatibility with the antigens of the target. The majority of glycobiology-specific antibodies are compatible with a variety of species.
AMSBIO also offers a wide range of specific enzymes to help with glycobiology research and other applications. The company offers a variety of glycosaminoglycan degrading enzymes including chondroitinase (heparinase) and hyaluronidase (hyaluronidase).
Heparanase and hyaluronidase play crucial roles in degrading carbohydrates in extracellular matrix. Chondroitinase ABC has been associated with plasticity and repair of neural cells. AMSBIO offers instruments to measure the activity of these enzymesin supernatants of cells, plasma and other biological fluids, and tissue samples. These kits are extensively utilized by leading research groups to study kidney disease, anti-inflammatory reactions and cancer, as they address the standardization and performance issues that are associated with traditional measurement methods for these kinds of enzymes.
For further information on advanced tools for glycobiology research please visit https://www.amsbio.com/research-areas/glycobiology or contact AMSBIO on+44-1235-828200 / +1-617-945-5033 / [email protected].
Content Source: https://www.news-medical.net/news/20211116/Advanced-tools-for-Glycobiology-research.aspx