Reflex app functions as pupillometers to detect concussion biomarkers

Assessing patients with concussions for recovery and determining the severity of their injuries is in a matter of making a video on a smartphone.

Reflex, a smartphone app developed by Purdue Foundry-affiliated startup Brightlamp, works as a pupillometer. It makes a digital recording of an eye to measure a response called pupillary light reflex. The user holds the camera up to an eye and then taps the smartphone screen. The pupil responds by flashing an LED. Reflex is a Class I 510(k) exempted regulated medical device, according to the U.S. Food and Drug Administration.

Doctors across North America used Reflex to perform a retrospective clinical review of patients treated in neurological clinics. The findings of the study were published in Life, an international, peer-reviewed open access journal that focuses on life sciences scientific studies.

Dr. Frederick Carrick, professor of neurology at the University of Central Florida College of Medicine said Reflex detects biomarkers that could be used in clinical diagnosis and treatment as well as in decision-making regarding concussions.

Physicians have measured pupillary light reflex since the earliest days of recorded history” Carrick. It has only been recently that we have been capable of quantifying it accurately thanks to technological advancements. This is the biggest study of concussion and PLR to date.”

Dr. Frederick Carrick, professor of neurology, University of Central Florida College of Medicine

Kurtis Sluss is the CEO and founder at brightlamp. He said that the study that was published in Life proves that Reflex is perfect for the clinical decision-making tools.

“We are accelerating the integration of this knowledge into a concussion-based clinical decision support measure that users of the present and future can utilize to keep track of their patients more closely,” Sluss said.

“Clinicians and trainers now have the proof they need to confidently integrate Reflex into their concussion treatment workflow. Our company’s goal is to maximize recovery from concussions and prevent injury from compounding to ensure that patients live healthier lives.

Sluss has received guidance in commercialization from the Purdue Foundry. This center for commercialization and entrepreneurship is located in the Convergence Center for Innovation and Collaboration located in the Discovery Park District at Purdue. It is situated near the Purdue campus. The company he founded is now part of the Purdue Foundry’s Double Down Experiment which includes high-growth companies.

Journal reference:

Carrick, F.R., et al. (2021) The Pupillary Light Reflex as a Biomarker of Concussion. Life.

Content Source:

Gemma Wilson

Gemma is a journalism graduate with keen interest in covering business news – specifically startups. She has as a keen eye for technologies and has predicted quite a few successful startups over the last couple of years.

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