$94 million PCORI funding to help fund the next phase of PCORnet and a new colorectal Cancer study of older adults

Today the Patient-Centered Outcomes Institute Board of Governors approved $61.3 million for a list of infrastructure projects that will support eight Clinical Research Networks (CRNs), in order to implement the next phase of PCORnet r, National Patient-Centered Clinical Research Network. The Board also approved the award of $32.7 million grant for a multi-phase comparative clinical effectiveness (CER) study that will evaluate colonoscopy and stool-based tests to monitor patients who are 70 or older with a low risk of developing colorectal cancer.

The Board also approved funding for a slate of awards that included the $2.1million project to help with the implementation a integrated online weight management program and support for population health management program that has been proven to be effective in an PCORI funded study.

Health-related decisions are made by people every day, decisions that ultimately are better informed by the evidence produced by research and projects funded by PCORI funds across the U.S. These awards are an excellent illustration of the variety of activities PCORI helps to assist patients, caregivers, clinicians, and other stakeholders in making these decisions in support for better health and care.

Nakela L. Cook, MD, MPH, PCORI Executive Director

$32.7 million for colorectal cancer screening study

Regular follow-up colonoscopies are commonly recommended for people who have had colon polyps identified. Due to the higher risk of complications that come with age, co-morbidities, and possibly a shorter life expectancy, those with small, low-risk polyps may not benefit from repeat colonoscopies.

A research team of the Dartmouth Institute for Health Policy & Clinical Practice, Kaiser Permanente Northern California Division of Research and Dartmouth Institute for Health Policy & Clinical Practice will recruit up to 15,310 English and Spanish-speaking patients ages between 70 and 82 at an array of U.S. sites. Patients will be randomly assigned to surveillance with either colonoscopy, or the annual Fecal Immunochemical test, which is a widely used, noninvasive screening option for patients who are at risk for colorectal cancer. Researchers will track the patients’ progress for five years throughout the study.

The funding award was made in accordance with an opportunity for funding from PCORI. It funds large multi-phase CER studies that fill in critical gaps in evidence. Under this funding opportunity, PCORI awarded $135 million in July to a slate of five research studies that focus on suicide prevention methods such as anesthesia blood pressure control, palliative care and diabetes medications for cancer patients.

$61.3 million to be used to implement PCORnet phase 3

The Board approved $61.3 million to help eight PCORnet CRNs optimize their infrastructure and capacity to support PCORnet’s third phase as a resource for the nation to conduct patient-centered, efficient and speedy research.

PCORI’s “network of networks”, PCORnet is a network that connects many major health care systems across the country. It provides access to research data, data, expertise, and patient insights to facilitate more patient-centered clinical research. PCORnet is crucial in assisting COVID-19 research that is funded by the National Institutes of Health and surveillance funding by the Centers for Disease Control and Prevention.

CRNs will ensure continuity and maximum use of resources and operations that were previously utilized in previous phases of the national network. Priorities include increasing the variety of patient populations and healthcare settings within PCORnet, efficiently conducting studies that address PCORI’s strategic research priorities, strengthening patient and stakeholder engagement, and providing high-quality data to power studies.

The CRNs who have been awarded funding include:

  • Accelerating the Value of Data across the National Community Health Center (ADVANCE) Collaborative
  • Greater Plains Collaborative (GPC)
  • INSIGHT Clinical Research Network
  • OneFlorida+ Clinical Research Consortium
  • PaTH Network
  • PEDSnet
  • Research Action for Health Network (REACHnet)
  • The Stakeholders, Technology and Researchers (STAR) Clinical Research Network

$2.1 million to support the implementation of the weight loss study results

Researchers at Brigham and Women’s Hospital have received $2.1 million in funding to implement an online weight loss program that has been demonstrated through PCORI-funded research. This will allow for more patients suffering from obesity or overweight in a variety care settings.

Details of these and other studies that were approved for funding by PCORI’s Board today are on the PCORI website. All funding awards were approved pending a business and programmatic review by PCORI staff and the announcement of formal contract agreements. PCORI has provided around $3.3 billion in donations to support patient-centered CER. It also supports other initiatives that help improve CER methods and the infrastructure needed to conduct CER efficiently and efficiently.

Research Institute Research on Patient-Centered Outcomes

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Gemma Wilson

Gemma is a journalism graduate with keen interest in covering business news – specifically startups. She has as a keen eye for technologies and has predicted quite a few successful startups over the last couple of years.

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